UPDATE 2-Inspector faults 14 Justice employees, clears Holder in gun probe

* Department's Inspector General finds no cover-up

* Two senior Justice officials leave after report issued

WASHINGTON, Sept 19 (Reuters) - The U.S. Justice

Department's internal watchdog faulted 14 federal employees on

Wednesday for the botched anti-gun-trafficking effort known as

"Operation Fast and Furious," prompting two senior officials to

leave the government but clearing Attorney General Eric Holder

of any wrongdoing.

Congressional Republicans during a series of hearings

investigating the failed operation sharply criticized Holder,

the nation's top law-enforcement official appointed by President

Barack Obama, during this year's presidential campaign. One U.S.

agent was killed in Arizona, potentially in connection with the

operation.

The new report from the department's Inspector General found

screw-ups of "systemic" scope that risked public safety but

found no cover-up, as charged by Republicans.

That, and a statement supportive of the report from Holder's

main Republican accuser, Representative Darrell Issa, seems

likely to defuse what could have been a politically explosive

conclusion to the probe.

Two senior department officials left the government as the

report was made public. Kenneth Melson, former head of the U.S.

agency that enforces gun laws, retired, while Jason Weinstein,

responsible for oversight of many criminal-related matters,

resigned.

The highest official to be criticized, Lanny Breuer, the

assistant attorney general in charge of criminal prosecutions,

has been "admonished," said a department official.

The book-length, 471-page report is the most in-depth look

yet at Operation Fast and Furious. It follows a 19-month review

by the department watchdog that had access to non-public

documents.

Fast and Furious began in 2009 as an effort to stop the flow

of firearms from Arizona to Mexican drug cartels. As U.S. agents

tried to build an expansive case, they did not pursue low-level

gun buyers who bought about 2,000 potentially illegal firearms

and trafficked many of them across the border.

The report said that Melson and Weinstein failed to ask

detailed questions about the tactics in Fast and Furious,

allowing the operation to go on in 2010 when they could have

stopped it, the report said.

'SPECULATIVE ASSUMPTIONS'

Melson said in a statement that he disagrees with parts of

the report that he called "speculative assumptions, conclusions

and characterizations," but he added, "I was ultimately

responsible for the actions of each employee."

Melson was pushed out in August 2011 as acting director of

the U.S. Bureau of Alcohol, Tobacco, Firearms and Explosives

(ATF) and recently worked on forensic policy for the department.

Weinstein wrote in a blistering resignation letter that the

inspector general's conclusion about him is "completely false."

"For me to have done this would have run counter to the

entire body of work I compiled during the past 15 years,"

Weinstein wrote, adding that he was singled out for blame

because of politicized congressional hearings.

Weinstein's boss, Breuer, was among those the inspector

general recommends for potential internal discipline.

Breuer should have alerted his superiors, including Holder,

in 2010 to flaws in a program similar to Fast and Furious that

was started during George W. Bush's presidency. Breuer said in a

congressional hearing in 2011 that not doing so "was a mistake"

and that he had regrets.

The 12 officials, including Gary Grindler, a former deputy

attorney general who is now Holder's chief of staff, could face

a wide range of discipline or none at all, depending on the

judgment of Justice Department and ATF authorities.

But at Justice headquarters at least, no further personnel

shake-ups are expected, one department official said.

VINDICATION FOR HOLDER

Holder pointed to the inspector general's report, which he

requested in February 2011, as vindication that he knew nothing

of the operation's tactics and did not try to cover them up.

"It is unfortunate that some were so quick to make baseless

accusations before they possessed the facts about these

operations - accusations that turned out to be without

foundation and that have caused a great deal of unnecessary harm

and confusion," he said in a statement.

He praised the newly departed officials, saying Weinstein

had "unwavering" commitment to the Justice Department.

In a rare show of agreement, Issa, the Republican who has

led a congressional inquiry into Fast and Furious, also found

reason to praise the inspector general's report. Issa said it

confirms the operation's "near total disregard for public

safety."

"It's time for President Obama to step in and provide

accountability for officials at both the Department of Justice

and ATF who failed to do their jobs," Issa said in a statement.

Fast and Furious came to light after the December 2010

shooting death of a U.S. Border Patrol agent, Brian Terry. Two

guns that firearms agents attempted to track were found at the

scene of Terry's death in rural Arizona.

The operation raised the fury of U.S. gun-rights advocates,

who helped to drive attention in Congress and the media.