UPDATE 5-Train ploughs into school bus in Egypt, 50 killed

* Almost all the dead were children, aged four to eight

* Poor safety record on roads and railways

* Transport minister resigns

(Adds comments from village where some children came from)

CAIRO, Nov 17 (Reuters) - Fifty people, mostly children,

were killed when a train slammed into a school bus as it crossed

the tracks at a rail crossing south of Cairo on Saturday,

further inflaming public anger at Egypt's shoddy transport

network.

Witnesses said barriers at the crossing were open when the

train hit the bus. Transport Minister Mohamed Rashad and the

head of the railways authority resigned, and President Mohamed

Mursi said those responsible would be held to account.

The bus was broken in half by the force of the crash. Blood

was spattered on the front of the engine and school bags and

text books, some bloodstained, were strewn around.

All but two of the dead were children, aged around four to

eight, said a senior security official in Assiut, near the crash

site. One woman and the bus driver also died, he said.

Egypt's roads and railways have a poor safety record and

Egyptians have long complained that successive governments have

failed to enforce even basic safeguards, leading to a string of

deadly crashes.

Prime Minister Hisham Kandil travelled to the area to review

the situation. But devastated and angry people in one village

from where the children had been picked up to travel to school

said they would bar entry to any visiting officials.

"We won't accept any officials in the village. They only

want to come to appear in the media," said Alaa Ahmed from

al-Hawatka, where some children killed on the bus came from.

They were travelling to a school near Manfalut, about 300 km

(190 miles) south of Cairo.

Some victims' families protested at the crash site. Many

other Egyptians across the nation were also shocked and angered.

"It is so shameful and a big disgrace to this government.

All of its members, and not only one minister, should quit. That

is what I know would happen in any decent country," said Mona

Ahmed, a 60-year-old mother of three, in Cairo.

BARRIERS OPEN

State media reported that as well as 50 dead, 15 or more

people were injured. A medical source said as many as 28 were

injured, 27 of them children.

"They told us the barriers were open when the bus crossed

the tracks and the train collided with it," said Mohamed Samir,

a doctor at Assiut hospital where the injured were taken, citing

witness accounts.

Assiut Governor Yahya Keshk also said the crossing was open.

"The crossing worker was asleep. He has been detained," he told

state television.

The doctor said the bodies of many of those killed were

severely mutilated, illustrating the force of the crash.

"I saw the train collide with the bus and push it about 1 km

(half a mile) along the track," said Ahmed Youssef, a driver.

Officials said the level of destruction and mutilation made

it difficult to count and identify the bodies.

Mursi ordered his ministers to offer support to the families

of those killed, the official news agency said.

Egypt's worst train disaster was in 2002 when a fire ripped

through seven carriages of an overcrowded passenger train,

killing at least 360 people.

At that time, when Mursi was an opposition member of

parliament for his Muslim Brotherhood group, he accused the then

prime minister and officials of "gross negligence".

Many more have been killed in rail accidents since then

despite pledges from successive governments to improve safety.

Earlier this month, at least three Egyptians were killed and

more than 30 injured in a train crash in Fayoum, another city

south of Cairo. In July, 15 people were injured in Giza, close

to the capital, when a train derailed.

Reflecting frustration at the state of public transport,

Cairo metro workers went on strike this week complaining about

poor levels of safety and maintenance.

Accidents involving multiple deaths are also common on

Egypt's poor quality roads. A crash on Cairo's outskirts on

Saturday involving a minibus killed at least 11 people, security

sources said.

(Additional reporting by Yasmine Saleh and Shaimaa Fayed;

Editing by Alison Williams)